/* * StructuredCoalescentSimulator.java * * Copyright (c) 2002-2015 Alexei Drummond, Andrew Rambaut and Marc Suchard * * This file is part of BEAST. * See the NOTICE file distributed with this work for additional * information regarding copyright ownership and licensing. * * BEAST is free software; you can redistribute it and/or modify * it under the terms of the GNU Lesser General Public License as * published by the Free Software Foundation; either version 2 * of the License, or (at your option) any later version. * * BEAST is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the * GNU Lesser General Public License for more details. * * You should have received a copy of the GNU Lesser General Public * License along with BEAST; if not, write to the * Free Software Foundation, Inc., 51 Franklin St, Fifth Floor, * Boston, MA 02110-1301 USA */ package dr.evolution.coalescent.structure; import dr.evolution.coalescent.DemographicFunction; import dr.evolution.colouring.ColourChangeMatrix; import dr.evolution.tree.SimpleNode; import dr.evolution.tree.SimpleTree; import dr.evolution.tree.Tree; import dr.evolution.util.TaxonList; import dr.evolution.util.TimeScale; /** * This class provides the basic engine for coalescent simulation of a given demographic model over a given time period. * * @author Andrew Rambaut * <p/> * $Id: StructuredCoalescentSimulator.java,v 1.7 2006/01/12 11:12:42 rambaut Exp $ */ public class StructuredCoalescentSimulator { public static final String COALESCENT_TREE = "structuredCoalescentTree"; public static final String COALESCENT_SIMULATOR = "structuredCoalescentSimulator"; public static final String ROOT_HEIGHT = "rootHeight"; public StructuredCoalescentSimulator() { } /** * Simulates a coalescent tree, given a taxon list. * * @param taxa the set of taxa to simulate a coalescent tree between * @param demoFunctions the demographic function to use */ public Tree simulateTree(TaxonList[] taxa, DemographicFunction[] demoFunctions, ColourChangeMatrix colourChangeMatrix) { SimpleNode[][] nodes = new SimpleNode[taxa.length][]; for (int i = 0; i < taxa.length; i++) { nodes[i] = new SimpleNode[taxa[i].getTaxonCount()]; for (int j = 0; j < taxa[i].getTaxonCount(); j++) { nodes[i][j] = new SimpleNode(); nodes[i][j].setTaxon(taxa[i].getTaxon(j)); } } dr.evolution.util.Date mostRecent = null; boolean usingDates = false; for (int i = 0; i < taxa.length; i++) { for (int j = 0; j < taxa[i].getTaxonCount(); j++) { if (TaxonList.Utils.hasAttribute(taxa[i], j, dr.evolution.util.Date.DATE)) { usingDates = true; dr.evolution.util.Date date = (dr.evolution.util.Date) taxa[i].getTaxonAttribute(j, dr.evolution.util.Date.DATE); if ((date != null) && (mostRecent == null || date.after(mostRecent))) { mostRecent = date; } } else { // assume contemporaneous tips nodes[i][j].setHeight(0.0); } } } if (usingDates) { assert mostRecent != null; TimeScale timeScale = new TimeScale(mostRecent.getUnits(), true, mostRecent.getAbsoluteTimeValue()); for (int i = 0; i < taxa.length; i++) { for (int j = 0; j < taxa[i].getTaxonCount(); j++) { dr.evolution.util.Date date = (dr.evolution.util.Date) taxa[i].getTaxonAttribute(j, dr.evolution.util.Date.DATE); if (date == null) { throw new IllegalArgumentException("Taxon, " + taxa[i].getTaxonId(j) + ", is missing its date"); } nodes[i][j].setHeight(timeScale.convertTime(date.getTimeValue(), date)); } if (demoFunctions[0].getUnits() != mostRecent.getUnits()) { //throw new IllegalArgumentException("The units of the demographic model and the most recent date must match!"); } } } return new SimpleTree(simulateCoalescent(nodes, demoFunctions, colourChangeMatrix)); } /** * @return the root node of the given array of nodes after simulation of the coalescent under the given demographic model. */ public SimpleNode simulateCoalescent(SimpleNode[][] nodes, DemographicFunction[] demographic, ColourChangeMatrix colourChangeMatrix) { SimpleNode[] rootNode = simulateCoalescent(nodes, demographic, colourChangeMatrix, 0.0, Double.POSITIVE_INFINITY); int attempts = 0; while (rootNode.length > 1 && attempts < 1000) { rootNode = simulateCoalescent(nodes, demographic, colourChangeMatrix, 0.0, Double.POSITIVE_INFINITY); attempts += 1; } if (rootNode.length > 1) { throw new RuntimeException(rootNode.length + " nodes found where there should have been 1, after 1000 tries!"); } return rootNode[0]; } public SimpleNode[] simulateCoalescent(SimpleNode[][] nodes, DemographicFunction[] demographic, ColourChangeMatrix colourChangeMatrix, double currentHeight, double maxHeight) { return null; } }