/*
* Licensed to the Apache Software Foundation (ASF) under one or more
* contributor license agreements. See the NOTICE file distributed with
* this work for additional information regarding copyright ownership.
* The ASF licenses this file to You under the Apache License, Version 2.0
* (the "License"); you may not use this file except in compliance with
* the License. You may obtain a copy of the License at
*
* http://www.apache.org/licenses/LICENSE-2.0
*
* Unless required by applicable law or agreed to in writing, software
* distributed under the License is distributed on an "AS IS" BASIS,
* WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
* See the License for the specific language governing permissions and
* limitations under the License.
*/
/* NOTICE
* This file was modified from its original to include one-sided mann whitney test
* for lesser and greater.
*/
package org.baderlab.csplugins.mannwhit; // had to change package name because we still include commons.math
import org.apache.commons.math3.distribution.NormalDistribution;
import org.apache.commons.math3.exception.ConvergenceException;
import org.apache.commons.math3.exception.MaxCountExceededException;
import org.apache.commons.math3.exception.NoDataException;
import org.apache.commons.math3.exception.NullArgumentException;
import org.apache.commons.math3.stat.ranking.NaNStrategy;
import org.apache.commons.math3.stat.ranking.NaturalRanking;
import org.apache.commons.math3.stat.ranking.TiesStrategy;
import org.apache.commons.math3.util.FastMath;
/**
* An implementation of the Mann-Whitney U test (also called Wilcoxon rank-sum test).
*
* @version $Id: MannWhitneyUTest.java 1416643 2012-12-03 19:37:14Z tn $
*/
public class MannWhitneyUTestSided {
public static enum Type {
TWO_SIDED, GREATER, LESS
}
/** Ranking algorithm. */
private NaturalRanking naturalRanking;
/**
* Create a test instance using where NaN's are left in place and ties get
* the average of applicable ranks. Use this unless you are very sure of
* what you are doing.
*/
public MannWhitneyUTestSided() {
naturalRanking = new NaturalRanking(NaNStrategy.FIXED,
TiesStrategy.AVERAGE);
}
/**
* Create a test instance using the given strategies for NaN's and ties.
* Only use this if you are sure of what you are doing.
*
* @param nanStrategy
* specifies the strategy that should be used for Double.NaN's
* @param tiesStrategy
* specifies the strategy that should be used for ties
*/
public MannWhitneyUTestSided(final NaNStrategy nanStrategy,
final TiesStrategy tiesStrategy) {
naturalRanking = new NaturalRanking(nanStrategy, tiesStrategy);
}
/**
* Ensures that the provided arrays fulfills the assumptions.
*
* @param x first sample
* @param y second sample
* @throws NullArgumentException if {@code x} or {@code y} are {@code null}.
* @throws NoDataException if {@code x} or {@code y} are zero-length.
*/
private void ensureDataConformance(final double[] x, final double[] y)
throws NullArgumentException, NoDataException {
if (x == null ||
y == null) {
throw new NullArgumentException();
}
if (x.length == 0 ||
y.length == 0) {
throw new NoDataException();
}
}
/** Concatenate the samples into one array.
* @param x first sample
* @param y second sample
* @return concatenated array
*/
private double[] concatenateSamples(final double[] x, final double[] y) {
final double[] z = new double[x.length + y.length];
System.arraycopy(x, 0, z, 0, x.length);
System.arraycopy(y, 0, z, x.length, y.length);
return z;
}
/**
* Computes the <a
* href="http://en.wikipedia.org/wiki/Mann%E2%80%93Whitney_U"> Mann-Whitney
* U statistic</a> comparing mean for two independent samples possibly of
* different length.
* <p>
* This statistic can be used to perform a Mann-Whitney U test evaluating
* the null hypothesis that the two independent samples has equal mean.
* </p>
* <p>
* Let X<sub>i</sub> denote the i'th individual of the first sample and
* Y<sub>j</sub> the j'th individual in the second sample. Note that the
* samples would often have different length.
* </p>
* <p>
* <strong>Preconditions</strong>:
* <ul>
* <li>All observations in the two samples are independent.</li>
* <li>The observations are at least ordinal (continuous are also ordinal).</li>
* </ul>
* </p>
*
* @param x the first sample
* @param y the second sample
* @return Mann-Whitney U statistic (maximum of U<sup>x</sup> and U<sup>y</sup>)
* @throws NullArgumentException if {@code x} or {@code y} are {@code null}.
* @throws NoDataException if {@code x} or {@code y} are zero-length.
*/
public double mannWhitneyU(final double[] x, final double[] y)
throws NullArgumentException, NoDataException {
ensureDataConformance(x, y);
final double[] z = concatenateSamples(x, y);
final double[] ranks = naturalRanking.rank(z);
double sumRankX = 0;
/*
* The ranks for x is in the first x.length entries in ranks because x
* is in the first x.length entries in z
*/
for (int i = 0; i < x.length; ++i) {
sumRankX += ranks[i];
}
/*
* U1 = R1 - (n1 * (n1 + 1)) / 2 where R1 is sum of ranks for sample 1,
* e.g. x, n1 is the number of observations in sample 1.
*/
final double U1 = sumRankX - (x.length * (x.length + 1)) / 2;
/*
* It can be shown that U1 + U2 = n1 * n2
*/
final double U2 = x.length * y.length - U1;
return FastMath.max(U1, U2);
}
/**
* Computes the Mann-Whitney
* U1 statistic</a> comparing mean for two independent samples possibly of
* different length.
* <p>
* Let X<sub>i</sub> denote the i'th individual of the first sample and
* Y<sub>j</sub> the j'th individual in the second sample. Note that the
* samples would often have different length.
* </p>
* <p>
* <strong>Preconditions</strong>:
* <ul>
* <li>All observations in the two samples are independent.</li>
* <li>The observations are at least ordinal (continuous are also ordinal).</li>
* </ul>
* </p>
*
* @param x the first sample
* @param y the second sample
* @return Mann-Whitney U statistic (maximum of U<sup>x</sup> and U<sup>y</sup>)
* @throws NullArgumentException if {@code x} or {@code y} are {@code null}.
* @throws NoDataException if {@code x} or {@code y} are zero-length.
*/
public double mannWhitneyU1(final double[] x, final double[] y)
throws NullArgumentException, NoDataException {
ensureDataConformance(x, y);
final double[] z = concatenateSamples(x, y);
final double[] ranks = naturalRanking.rank(z);
double sumRankX = 0;
/*
* The ranks for x is in the first x.length entries in ranks because x
* is in the first x.length entries in z
*/
for (int i = 0; i < x.length; ++i) {
sumRankX += ranks[i];
}
/*
* U1 = R1 - (n1 * (n1 + 1)) / 2 where R1 is sum of ranks for sample 1,
* e.g. x, n1 is the number of observations in sample 1.
*/
final double U1 = sumRankX - (x.length * (x.length + 1)) / 2;
return U1;
}
/**
* @param Umin smallest Mann-Whitney U value
* @param Umin smallest Mann-Whitney U1 value
* @param Umin smallest Mann-Whitney U2 value
* @param n1 number of subjects in first sample
* @param n2 number of subjects in second sample
* @return two-sided asymptotic p-value
* @throws ConvergenceException if the p-value can not be computed
* due to a convergence error
* @throws MaxCountExceededException if the maximum number of
* iterations is exceeded
*/
private double calculateAsymptoticPValue(final double Umin,
final double U1,
final double U2,
final int n1,
final int n2,
final Type side)
throws ConvergenceException, MaxCountExceededException {
/* long multiplication to avoid overflow (double not used due to efficiency
* and to avoid precision loss)
*/
final long n1n2prod = (long) n1 * n2;
// http://en.wikipedia.org/wiki/Mann%E2%80%93Whitney_U#Normal_approximation
final double EU = n1n2prod / 2.0;
final double VarU = n1n2prod * (n1 + n2 + 1) / 12.0;
final double z = (Umin - EU) / FastMath.sqrt(VarU);
// No try-catch or advertised exception because args are valid
final NormalDistribution standardNormal = new NormalDistribution(0, 1);
double p = 2 * standardNormal.cumulativeProbability(z);
if(side == Type.TWO_SIDED) {
return p;
}
if(side == Type.LESS) {
if(U1 < U2) {
return 0.5 * p;
} else {
return 1.0 - (0.5 * p);
}
} else {
if(U1 > U2) {
return 0.5 * p;
} else {
return 1.0 - (0.5 * p);
}
}
}
/**
* Returns the asymptotic <i>observed significance level</i>, or <a href=
* "http://www.cas.lancs.ac.uk/glossary_v1.1/hyptest.html#pvalue">
* p-value</a>, associated with a <a
* href="http://en.wikipedia.org/wiki/Mann%E2%80%93Whitney_U"> Mann-Whitney
* U statistic</a> comparing mean for two independent samples.
* <p>
* Let X<sub>i</sub> denote the i'th individual of the first sample and
* Y<sub>j</sub> the j'th individual in the second sample. Note that the
* samples would often have different length.
* </p>
* <p>
* <strong>Preconditions</strong>:
* <ul>
* <li>All observations in the two samples are independent.</li>
* <li>The observations are at least ordinal (continuous are also ordinal).</li>
* </ul>
* </p><p>
* Ties give rise to biased variance at the moment. See e.g. <a
* href="http://mlsc.lboro.ac.uk/resources/statistics/Mannwhitney.pdf"
* >http://mlsc.lboro.ac.uk/resources/statistics/Mannwhitney.pdf</a>.</p>
*
* @param x the first sample
* @param y the second sample
* @return asymptotic p-value
* @throws NullArgumentException if {@code x} or {@code y} are {@code null}.
* @throws NoDataException if {@code x} or {@code y} are zero-length.
* @throws ConvergenceException if the p-value can not be computed due to a
* convergence error
* @throws MaxCountExceededException if the maximum number of iterations
* is exceeded
*/
public double mannWhitneyUTest(final double[] x, final double[] y, Type side)
throws NullArgumentException, NoDataException,
ConvergenceException, MaxCountExceededException {
ensureDataConformance(x, y);
final double Umax = mannWhitneyU(x, y);
/*
* It can be shown that U1 + U2 = n1 * n2
*/
final double Umin = x.length * y.length - Umax;
//we require the U1 and U2 values in order to determine which p-value to calculate for the sided tests
final double U1 = mannWhitneyU1(x, y);
final double U2 = x.length * y.length - U1;
return calculateAsymptoticPValue(Umin, U1, U2, x.length, y.length, side);
}
}